6,878 research outputs found

    The education and practice gap of accounting

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    Educators nowadays may equip students for jobs that will not exist in the future (Shusterman, 2015) or jobs that do not exist yet. Many students face confession after graduating from tertiary education. Not knowing what to expect, wondering if they can use what they learn from school at work (Elmes, 2017). This paper aims to gather the opinion of accounting students regarding what they think are the demanded skills to get an accounting job after the completion of education. After reviewing the literature, a questionnaire was produced and sent to students at a tertiary institute to gain their opinion. Results were then compared to the skills required in practice by employers when recruiting. The key findings this study obtained were that there is a gap between what soft skills students think is important for an accounting position compared to that of practitioners’ view as stated by other researchers. Results indicate there is little difference of required hard skills (accounting techniques) from view points of students and professionals. Further studies should be done with larger samples to generalise more widely. Recommendations are that tertiary schools can partner with local business and accounting firms to provide internship program for all accounting major students. Also students should communicate with other accounting students, possible seniors or past students to gain their thoughts on what is currently lacking in the school education

    A CGE-Model Analysis of U.S. Imposed Automotive Tariffs

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    Using a computable generable equilibrium (CGE) model, this research paper evaluates the effects of a U.S. imposed 25% automotive import tariff on NAFTA countries and the European Union, the greatest U.S. automotive trade partners. Three simulations were conducted: the implementation of tariffs with no retaliation, equivalent retaliation on the same products, and retaliation on the top exports of politically significant states, with sensitivity analysis applied in the final scenario. The results demonstrate that the EU is marginally affected while the NAFTA countries experience the greatest increases in prices and reduction in total wages

    Simplifying NASA Earth Science Data and Information Access Through Natural Language Processing Based Data Analysis and Visualization

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    NASA Earth science data collected from satellites, model assimilation, airborne missions, and field campaigns, are large, complex and evolving. Such characteristics pose great challenges for end users (e.g., Earth science and applied science users, students, citizen scientists), particularly for those who are unfamiliar with NASA's EOSDIS and thus unable to access and utilize datasets effectively. For example, a novice user may simply ask: what is the total rainfall for a flooding event in my county yesterday? For an experienced user (e.g., algorithm developer), a question can be: how did my rainfall product perform, compared to ground observations, during a flooding event? Nonetheless, with rapid information technology development such as natural language processing, it is possible to develop simplified Web interfaces and back-end processing components to handle such questions and deliver answers in terms of text, data, or graphic results directly to users.In this presentation, we describe the main challenges for end users with different levels of expertise in accessing and utilizing NASA Earth science data. Surveys reveal that most non-professional users normally do not want to download and handle raw data as well as conduct heavy-duty data processing tasks. Often they just want some simple graphics or data for various purposes. To them, simple and intuitive user interfaces are sufficient because complicated ones can be difficult and time-consuming to learn. Professionals also want such interfaces to answer many questions from datasets. One solution is to develop a natural language based search box like Google and the search results can be text, data, graphics and more. Now the challenge is, with natural language processing, can we design a system to process a scientific question typed in by a user? In this presentation, we describe our plan for such a prototype. The workflow is: 1) extract needed information (e.g., variables, spatial and temporal information, processing methods, etc.) from the input, 2) process the data in the backend, and 3) deliver the results (data or graphics) to the user

    Bio-templated Substrates for Biosensor Applications

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    Nanopatterning of materials is of particular interest for applications in biosensors, microfluidics, and drug delivery devices. In biosensor applications there is a need for rapid, low cost, and durable system for detection. This dissertation aims to investigate methods to pattern nanostructured surfaces using virus particles as templates. The virus species used in these experiments is a cysteine modified tobacco mosaic virus. The first project utilized the lamellar microphase separation of a block copolymer to pattern the virus particles. Although microphase separation of the poly(styrene-b-2-vinylpyridine) (PS-P2VP) into lamellae was confirmed, specificity of the viruses to the gold doped block of the polymer could not be achieved. Single virus particles lay across multiple lamellae and aggregated in side-to-side and head-to-tail arrangements. The second project studied the effect of a surfactant on virus assembly onto a gold chip. The experiments included placing a gold chip in virus solutions with varying triton concentrations (0-0.15%), then plating the virus particles with a metal. Results showed that as the triton concentration in the virus solution increases, the virus density on the surface decreases. The gold coated virus particles were applied to Surface Enhanced Raman Spectroscopy (SERS) detection in the final project. SERS is of interest for biosensor applications due to its rapid detection, low cost, portability, and label-free characteristics. In recent years, it has shown signal enhancement using gold, silver, and copper nanoparticles in solutions and on roughened surfaces. The gold plated virus surfaces were tested as SERS substrates using R6G dye as the analyte. An enhancement factor (EF) of 10^4 was seen in these samples versus the non-SERS substrate. This corresponded to the sample with 0.05% triton in the virus solution which showed the most intersection points between the virus particles and the most uniform coverage of the viruses on the surface. This value is lower than that of previous studies; however, future work may be performed to optimize conditions to achieve the highest signal possible

    The Early Progenitors of Mouse Dendritic Cells and Plasmacytoid Predendritic Cells Are within the Bone Marrow Hemopoietic Precursors Expressing Flt3

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    Flt3 ligand (Flt3L) is a growth factor for hemopoietic progenitors and can promote the expansion of both conventional dendritic cells (DCs) and plasmacytoid predendritic cells (p-preDCs). The cells responding to Flt3L treatment and the precursors for the DCs and p-preDCs had not been fully characterized. We examined different mouse bone marrow (BM) hemopoietic precursor populations for the surface expression of Flt3 and tested them for early DC and p-preDC precursor activity. Most DC precursor activity, other than that given by multipotent hemopoietic stem cells, was within the downstream precursors expressing Flt3. The majority of mouse BM common lymphoid precursors expressed high levels of Flt3 and these were the most efficient precursors of both DCs and p-preDCs. In contrast, only a small proportion of the common myeloid precursors (CMPs) expressed Flt3, but the precursor activity for both DCs and p-preDCs was within this minor Flt3+ CMP fraction. The granulocyte and macrophage precursors and pro-B cells did not express Flt3 and had no DC or p-preDC precursor activity. These findings demonstrate that the early precursors for all DC subtypes are within the BM Flt3+ precursor populations, regardless of their lymphoid or myeloid lineage orientation

    Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin

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    Background: Changes in cellular phenotype result from underlying changes in mRNA transcription and translation. Endothelin-1 stimulates cardiomyocyte hypertrophy with associated changes in mRNA/protein expression and an increase in the rate of protein synthesis. Insulin also increases the rate of translation but does not promote overt cardiomyocyte hypertrophy. One mechanism of translational regulation is through 5' terminal oligopyrimidine tracts (TOPs) that, in response to growth stimuli, promote mRNA recruitment to polysomes for increased translation. TOP mRNAs include those encoding ribosomal proteins, but the full panoply remains to be established. Here, we used microarrays to compare the effects of endothelin-1 and insulin on the global transcriptome of neonatal rat cardiomyocytes, and on mRNA recruitment to polysomes (i.e. the translatome). Results: Globally, endothelin-1 and insulin (1 h) promoted >1.5-fold significant (false discovery rate 1.25-fold significant changes in expression in total and/or polysomal RNA induced by endothelin-1 or insulin, respectively, of which ~35% of endothelin-1-responsive and ~56% of insulin-responsive transcripts were translationally regulated. Of mRNAs for established proteins recruited to polysomes in response to insulin, 49 were known TOP mRNAs with a further 15 probable/possible TOP mRNAs, but 49 had no identifiable TOP sequences or other consistent features in the 5' untranslated region. Conclusions: Endothelin-1, rather than insulin, substantially affects global transcript expression to promote cardiomyocyte hypertrophy. Effects on RNA recruitment to polysomes are subtle, with differential effects of endothelin-1 and insulin on specific transcripts. Furthermore, although insulin promotes recruitment of TOP mRNAs to cardiomyocyte polysomes, not all recruited mRNAs are TOP mRNAs
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